The Sewanee Domain is located at the southern end of the Cumberland Plateau which extends down through Kentucky into Tennessee and Alabama. It is the westernmost portion of the Southern Appalachian region. The biologically rich hardwood forests of the Cumberland Plateau are considered to be among the highest conservation-value forests remaining in North America today. This is partly due to the fact that this region contains some of the largest remaining tracts of privately owned, contiguous temperate deciduous forest left on the continent.
What makes the landscape of the Domain such a unique educational asset for the study of the environment is the continuum that exists via the human-built environment extending into the natural environment.